She was a sister of John Greenlee, the founder of the Scottish Settlement in Northern Illinois. It was this family who sheltered John Greenlee and helped him in his escape to the United States.²

Isabelle died 14 February 1879 in Caledonia Townsip, Boone Co., Illinois

They emigrated to U.S.A. in 1850,³ leaving Campbeltown for Greenock and Glasgow to take the ship Charlotte Harrison, under Captain MacKintyre. They left for New York on 6 June 1850 with two sons and six daughters.

During the voyage they passed through a severe storm and were ordered to stay below with closed hatches. They found New York was holding memorial services with flags at half mast and the streets lined with soldiers because of President Zachary Taylor's death on July 9th.

Isabelle and her family settled on a farm on Quail Trap Rd. on the north side of the Argyle Settlement.⁴ .

• Children:^{5, 6}
• 1) Alexander: born 15 Jan. 1820, at Newton, Southend Parish, Scotland; married Margaret McKerral of Brunericken 28 Dec. 1843 in Southend.
• 2) Martha: born 16 Sept. 1822, Southend Village.
• 3) George: born 22 June 1825, Auchrua, Southend; married Margaret McPhail.
• 4) Janet: born 26 Jan. 1828, Achrua, Southend.
• 5) Mary: born 29 June 1830, Achrua Southend.
• 6) Isabella: born 13 Dec. 1832, Achrua, Southend.
• +7) Jean (Jane): born 16 Apr. 1835, Achrua Southend; married Thos. Ralston. They had seven children. The parish birth records give her name as Jean but family records show Jane.
• 8) Ann Helen: born 6 Jul. 1838, Achrua, Southend.
• 9) Elizabeth: born 13 Oct. 1843, Achrua, Southend.